This prospective longitudinal study will be conducted in patients diagnosed with Sjögren's disease who are followed at the rheumatology outpatient clinic of Kahramanmaras Sutcu Imam University Medical Faculty Hospital. Demographic and clinical data will be collected from routine clinical assessments and medical records, including laboratory results obtained during standard care.
Participants will undergo evaluation of pressure pain threshold using a digital algometer and complete validated questionnaires assessing fatigue, disease activity, patient-reported symptoms, anxiety and depression, pain catastrophizing, sleep quality, and physical activity level.
All assessments will be performed at baseline and repeated at follow-up visits approximately 3 months later.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosis of Sjögren's syndrome
* Age ≥ 18 years
* Willingness to participate and provide written informed consent
Exclusion Criteria:
* Presence of severe somatic or psychiatric disorders
* Presence of malignancy
* Pregnancy
* Refusal to participate or inability to provide written informed consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is specifically about understanding fatigue in Sjögren's disease — since fatigue is one of my biggest challenges, could you help me understand whether joining a 3-month observational study like this might give us better insight into what's driving my fatigue personally?
2The trial uses something called the Multidimensional Fatigue Inventory-20 to track fatigue over 3 months — can you explain what that questionnaire actually measures, and whether the findings from my participation could inform how we manage my symptoms going forward?
3Since this appears to be an observational study rather than a treatment trial, does that mean there's no experimental drug or therapy involved, and would participating in any way affect or delay my current treatment plan?
4This study is looking for explanatory factors and predictors of fatigue, which suggests they don't yet fully understand why Sjögren's patients experience fatigue — does that match where the research currently stands, and are there already any evidence-based options we should be trying for my fatigue while this kind of research is ongoing?
5What would my commitment look like over the 3 months — how many visits, assessments, or check-ins would be involved — and do you think that level of participation is realistic given everything else I'm managing with my condition?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.