RecruitingNot Applicable

Breathing Patterns in Infants Before and After Extubation

United States30 participantsStarted 2025-04-14

Plain-language summary

The primary objective of this study is to compare work of breathing indices before and after extubation in intubated premature infants admitted to the Christiana Care Neonatal Intensive Care Unit. The secondary objective is to compare the ability of work of breathing indices to predict extubation failure to routine spontaneous breathing tests (SBTs) in intubated premature infants admitted to the ChristianaCare NICU.

Who can participate

Age range0 Days – 6 Months

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * premature infants (born at ≤32 weeks gestation) who are intubated. * medical team is evaluating the baby for extubation readiness Exclusion Criteria: * Infants with skeletal, neuromuscular, or abdominal surgical disorders that affect the accuracy of RIP measurements will be excluded.

What they're measuring

Work of breathing before and after extubation

Timeframe: 25 minutes

Trial details

NCT IDNCT07542301

SponsorChristiana Care Health Services

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-10

Contact for this trial

Kelley Z. Kovatis, MD

302-301-2410 kelley.kovatis@christianacare.org

View on ClinicalTrials.gov More Respiratory Distress Syndrome (RDS) trials