CompletedNot Applicable

Comparison of Propofol and Propofol-Ketamine Anesthesia on Optic Nerve Sheath Diameter in Endovascular Cerebral Aneurysm Procedures

Turkey (Türkiye)46 participantsStarted 2025-06-15

Plain-language summary

This study aimed to compare the effects of propofol-based anesthesia and propofol-ketamine anesthesia on optic nerve sheath diameter (ONSD) in patients undergoing elective endovascular treatment of unruptured intracranial aneurysms. ONSD, measured using ultrasonography, is a non-invasive surrogate marker of intracranial pressure. In addition, intraoperative hemodynamic parameters, cerebral oxygenation, and anesthetic requirements were evaluated to assess the safety and physiological impact of the two anesthesia techniques.

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age between 18 and 75 years * Patients scheduled for elective endovascular treatment of unruptured intracranial aneurysms * ASA physical status I-III * Glasgow Coma Scale score of 15 * Ability to read and write and provide written informed consent Exclusion Criteria: * Age under 18 or over 75 years * ASA physical status IV or higher * History of ocular disease or previous eye surgery * Presence of giant aneurysm * Increased intracranial pressure * Coronary artery disease * Psychiatric or neurological disorders interfering with consent or assessment * Emergency surgical indication

What they're measuring

Change in Optic Nerve Sheath Diameter (ONSD)

Timeframe: From pre-induction (baseline) to end of procedure

Trial details

NCT IDNCT07542015

SponsorAnkara City Hospital Bilkent

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-12-20

View on ClinicalTrials.gov More Unruptured Intracranial Aneurysm trials