The Effects of Palm Olein and Palm Kernel Oil Diets on Gut Hormones and Appetite in Healthy Adults (NCT07541300) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
The Effects of Palm Olein and Palm Kernel Oil Diets on Gut Hormones and Appetite in Healthy Adults
Malaysia36 participantsStarted 2026-01-12
Plain-language summary
The goal of this clinical trial is to investigate the postprandial effect of palm olein- and palm kernel oil- diets compared to PUFA-rich diet (sunflower oil in this study) on gut hormones response and appetite in healthy adults. The main questions it aims to answer are:
• Do palm olein- and palm kernel oil-diets postulate to improve satiety and lower appetite compared to PUFA rich diet (sunflower oil) in healthy adults? Researchers will compare diets prepared with palm olain or palm kernel oil to a diet prepared with sunflower oil to see the effects of these three diets on gut hormones and satiety score.
Participants will:
* Attend a health screening session for subjects selection according to inclusion and exclusion criteria.
* Visit the study center three times with 2 weeks apart.
* Provide blood samples and fill up questionnaires at different time point within 4 hours.
* Receive a ad libitum meal after 4 hours intervention.
Who can participate
Age range
20 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 20 to 45 years.
* BMI 20 to 27.5 kg/m2.
* Blood pressure with 90 to 130 mmHg for systolic and 60 to 80 mmHg for diastolic measurements.
* Fasting blood glucose of 3.9 to 5.5 mmol/L.
* Fasting total cholesterol \< 6.0 mmol/L.
* Fasting triglycerides \< 2.3 mmol/L.
* Not using any form of nicotine and alcohol.
Exclusion Criteria:
* Diagnosed any form of heart disease, hypertension, diabetes mellitus, and metabolic syndrome with or without medication.
* Consuming any long term prescribed medications or supplements, including hormonal contraceptive pills.
* Having moderate anaemia with haemoglobin \<110 g/l for men and \<100 g/l for women.
* Having blood clotting problem
* Having difficulty in cannulation (small, thin or hard-to-find veins)
* Women who are pregnant or lactating.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.