Lower Intersecting HIV-related Stigmas to Facilitate Treatment as Prevention (LIFT) (NCT07541131) | Clinical Trial Compass
By InvitationNot Applicable
Lower Intersecting HIV-related Stigmas to Facilitate Treatment as Prevention (LIFT)
Kyrgyzstan80 participantsStarted 2026-02-09
Plain-language summary
The purpose of this study is to reduce HIV transmission risk among people who inject drugs (PWID) through a multilevel intervention known as LIFT. LIFT intervenes to build intragroup PWID support at the community-level to reduce overall drug use and stigma. LIFT also increases efficacy in navigating HIV services in the presence of structural stigma. Additionally, LIFT intervenes on abstinence-based drug use stigma at the health facility-level to improve clinic policy and staff interactions with clients.
This is an implementation study to adapt and pilot a stigma reduction intervention with persons who inject drugs (PWID) in Kyrgyzstan. The intervention includes peer-led group sessions focused on stigma reduction and providing support to increase HIV prevention efficacy. The aim will be to adapt, refine, and pilot the intervention among PWID and methadone maintenance treatment (MMT) clinic staff. Participants will be randomized to the intervention or control arms.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. reports injecting drugs or using drugs with someone who was injecting in the past 12 months before enrollment,
✓. is currently using illicit drugs (salts, synthetics, pharmaceuticals or opioids) including poly drug use,
✓. ≥ 18 years old,
✓. live in one of the two eligible districts
✓. report no intentions to move from Bishkek in the next 18 months,
✓. baseline rapid HIV test confirming HIV-negative status, and
✓. agree to participate in all intervention and assessment activities.
✓. ≥ 18 years old,
Exclusion criteria
✕. initiated injection drug use in the past 6 months,
✕. intend to move outside Bishkek in the next 18 months,
✕. do not agree to participate in all community-level intervention activities (i.e., five peer-led group sessions, four survey assessments over 18 months), or are confirmed to be living with HIV by self-report or baseline rapid test.