The Aim of the Present Study is to Determine Outcome Predictors in Children Who Were Diagnosed as Acute Disseminated Encephalomyelitis (ADEM).

Inclusion Criteria: * Children aged from 6 months old to 18 years. * Presence of clinical signs of acute encephalopathy with multifocal neurological deficits. * MRI findings suggestive of demyelinating lesions. Exclusion Criteria: * Pediatric patients diagnosed who were as multiple sclerosis. * Pediatric patients with clinical signs and radiological findings suggestive of neuromyelitis optica spectrum disorder. * Pediatric patients with infectious encephalitis. * Pediatric patients with metabolic or genetic neurological disorders