Serratus Posterior Superior Intercostal Plane Block Versus Intrathecal Morphine in VATs (NCT07540104) | Clinical Trial Compass
RecruitingNot Applicable
Serratus Posterior Superior Intercostal Plane Block Versus Intrathecal Morphine in VATs
Turkey (Türkiye)60 participantsStarted 2026-04-15
Plain-language summary
This study aims to compare the analgesic effects of the serratus posterior superior intercostal plane block and intrathecal morphine in patients undergoing video-assisted thoracoscopic surgery.
This is a prospective, randomized, controlled, single-center clinical trial including adult patients undergoing elective thoracoscopic surgery. Participants will be randomly assigned to receive either a serratus posterior superior intercostal plane block or intrathecal morphine before general anesthesia.
The primary outcome is cumulative opioid consumption during the first 24 postoperative hours, expressed as intravenous morphine milligram equivalents. Secondary outcomes include pain scores, time to first analgesic request, quality of recovery, and postoperative complications.
The study aims to determine whether these two techniques differ in their effectiveness for postoperative pain management.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age between 18 and 75 years
* American Society of Anesthesiologists physical status I to III
* Scheduled for elective video-assisted thoracoscopic surgery including wedge resection, segmentectomy, or lobectomy
Exclusion Criteria:
* Refusal to participate
* Pregnancy
* Morbid obesity (body mass index greater than 40 kg per square meter)
* Allergy to opioids, local anesthetics, or nonsteroidal anti-inflammatory drugs
* Neuropsychiatric disorders, cognitive impairment, or inability to communicate
* History of substance abuse
* Use of anticoagulant therapy or presence of bleeding disorders
* Active systemic infection
* Severe cardiovascular, hepatic, renal, or endocrine disease
* Chronic pain syndrome or ongoing chronic pain treatment
* Emergency surgery or prior ipsilateral thoracic surgery
* Preoperative opioid use
* Significant intraoperative or postoperative bleeding or hemodynamic instability
* Requirement for prolonged postoperative mechanical ventilation longer than 18 hours
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Cumulative opioid consumption within 24 hours after surgery