RecruitingNot Applicable

Effects of Menstrual Cycle on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery

Turkey (Türkiye)110 participantsStarted 2026-04-20

Plain-language summary

This observational study aims to evaluate the effect of menstrual cycle phase on optic nerve sheath diameter (ONSD) in women undergoing elective laparoscopic gynecologic surgery. Patients will be grouped according to menstrual cycle phase as follicular or luteal. ONSD measurements will be performed perioperatively, and postoperative nausea and vomiting as well as postoperative cognitive function will also be assessed. The study is designed to investigate whether hormonal variations during the menstrual cycle are associated with differences in intracranial pressure reflected by ONSD measurements and postoperative outcomes

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female patients aged 18 to 45 years * Scheduled for elective laparoscopic gynecologic surgery * Menstrual cycle in the follicular phase or luteal phase * American Society of Anesthesiologists (ASA) physical status I-II Exclusion Criteria: * Irregular menstrual cycle (e.g., polycystic ovary syndrome, early menopause, hypothalamic amenorrhea) * Pregnancy or breastfeeding * Neurological disease associated with intracranial pressure changes * Glaucoma or another eye disease associated with high intraocular pressure * Previous brain surgery * Uncontrolled hypertension or severe cardiovascular disease

What they're measuring

Optic Nerve Sheath Diameter

Timeframe: Before induction of anesthesia, during surgery, and at the end of surgery

Trial details

NCT IDNCT07539831

SponsorKonya City Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-03-03

Contact for this trial

MAHMUT TUTAR, MD

905552723704 masatu42@gmail.com