Active — Not RecruitingNot Applicable

Effectiveness of Dexamethasone Injection for Reducing Pain After Third Molar Surgery

Pakistan70 participantsStarted 2025-12-01

Plain-language summary

This randomized clinical trial aims to evaluate the effectiveness of dexamethasone injection in reducing postoperative pain after surgical removal of impacted mandibular third molars. Patients are divided into two groups: one receiving standard local anesthesia, and the other receiving an additional dexamethasone injection postoperatively. Pain levels are assessed using the Visual Analogue Scale (VAS) at 24, 48, and 72 hours after surgery. The study is conducted at 28 Military Dental Centre, Lahore.

Who can participate

Age range20 Years – 40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged 20 to 40 years * Patients with at least one impacted mandibular third molar (Class A or B, Class I or II) including mesioangular, horizontal, vertical, or distoangular impactions according to Pell and Gregory classification confirmed by panoramic radiograph * Patients with no systemic disease (e.g., diabetes mellitus, hypertension, ischemic heart disease) * Patients of either gender Exclusion Criteria: * Patients who have used analgesics or related drugs within 15 days prior to surgery * Pregnant patients * Patients with known allergy to corticosteroids * Patients with tooth associated with cyst, tumor, or trauma

What they're measuring

Postoperative pain intensity

Timeframe: 24 hours, 48 hours, and 72 hours postoperatively

Trial details

NCT IDNCT07538375

Sponsor28 Military Dental Centre Lahore

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2026-05-15

View on ClinicalTrials.gov More Impacted Mandibular Third Molar trials