Effects of Sleep Quality on Functional and Cognitive Outcomes in Multiple Sclerosis (NCT07536503) | Clinical Trial Compass
RecruitingNot Applicable
Effects of Sleep Quality on Functional and Cognitive Outcomes in Multiple Sclerosis
Turkey (Türkiye)80 participantsStarted 2026-05-01
Plain-language summary
The goal of this observational study is to investigate the effects of sleep quality on cognitive flexibility, physical activity level, body awareness, and reaction time in individuals with Multiple Sclerosis.
The main question it aims to answer is:
Does sleep quality influence cognitive flexibility, physical activity level, body awareness, and reaction time in individuals with Multiple Sclerosis?
Researchers will compare individuals with good and poor sleep quality to determine whether differences in sleep quality result in variations in cognitive and physical performance outcomes.
Participants will complete standardized assessments of sleep quality, cognitive flexibility, physical activity, and body awareness, and will perform a computer-based reaction time test. In addition, participants will wear a wearable activity tracker for 7 days to objectively measure physical activity levels.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age between 18 and 65 years
* Diagnosis of Multiple Sclerosis
* Montreal Cognitive Assessment (MoCA) score ≥24
* Expanded Disability Status Scale (EDSS) score between 0 and 6.5
* No relapse within the last 3 months
* Voluntary participation with written informed consent
Exclusion Criteria:
* Presence of other neurological, psychiatric, or systemic diseases
* Severe visual, auditory, or balance impairments
* History of surgery within the last 6 months
* Use of sleep medication or central nervous system-affecting drugs
* Severe orthopedic deformity or pain
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Sleep Quality (Pittsburgh Sleep Quality Index)
Timeframe: Baseline
2
Cognitive Flexibility (Stroop Test, TBAG Form)
Timeframe: Baseline
3
Physical Activity Level (International Physical Activity Questionnaire-Short Form)