Low-Flow Anesthesia Without Wash-in: Effects on Oxygenation and Depth of Anesthesia (NCT07534839) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Low-Flow Anesthesia Without Wash-in: Effects on Oxygenation and Depth of Anesthesia
Turkey (Türkiye)60 participantsStarted 2026-03-01
Plain-language summary
This study aims to evaluate whether adjusting the fresh gas flow rate to low-flow immediately after intubation, without performing a wash-in, is a reliable approach with respect to depth of anesthesia and oxygenation.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* ASA physical status I-II
* Cases lasting longer than 30 minutes
* Non-laparoscopic surgical procedures
Exclusion Criteria:
* Patients with life-threatening renal, cardiac, or hepatic disease
* Patients with chronic pulmonary diseases such as asthma or COPD
* Patients with intraoperative hemodynamic instability
* Patients with a body mass index (BMI) lower than 20 or higher than 30
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Comparison of arterial oxygen partial pressure (PaO₂) values between groups
Timeframe: Measured at 10, 20, 30, and 45 minutes after induction of anesthesia and before the end of surgery.
2
Comparison of Patient State Index (PSI) values between groups.
Timeframe: Continuously monitored intraoperatively and recorded at 10, 20, 30, and 45 minutes after induction of anesthesia.