Active — Not RecruitingNot Applicable

Low-Flow Anesthesia Without Wash-in: Effects on Oxygenation and Depth of Anesthesia

Turkey (Türkiye)60 participantsStarted 2026-03-01

Plain-language summary

This study aims to evaluate whether adjusting the fresh gas flow rate to low-flow immediately after intubation, without performing a wash-in, is a reliable approach with respect to depth of anesthesia and oxygenation.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ASA physical status I-II * Cases lasting longer than 30 minutes * Non-laparoscopic surgical procedures Exclusion Criteria: * Patients with life-threatening renal, cardiac, or hepatic disease * Patients with chronic pulmonary diseases such as asthma or COPD * Patients with intraoperative hemodynamic instability * Patients with a body mass index (BMI) lower than 20 or higher than 30

What they're measuring

Comparison of arterial oxygen partial pressure (PaO₂) values between groups

Timeframe: Measured at 10, 20, 30, and 45 minutes after induction of anesthesia and before the end of surgery.

Comparison of Patient State Index (PSI) values between groups.

Timeframe: Continuously monitored intraoperatively and recorded at 10, 20, 30, and 45 minutes after induction of anesthesia.

Trial details

NCT IDNCT07534839

SponsorErzincan Binali Yildirim Universitesi

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07-01

View on ClinicalTrials.gov More Low Flow Anesthesia trials