The study has 2 groups, one each focusing on co-administration of elecoglipron and atorvastatin or rosuvastatin to assess the pharmacokinetics (PK) of atorvastatin in healthy participants.
Age range
18 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Area under concentration-time curve from time 0 to infinity (AUCinf) of atorvastatin
Timeframe: Group 1: Day 1 to Day 71
Area under concentration-curve from time 0 to the last quantifiable concentration (AUClast) of atorvastatin
Timeframe: Group 1: Day 1 to Day 71
Maximum observed drug concentration (Cmax) of atorvastatin
Timeframe: Group 1: Day 1 to Day 71
AUCinf of rosuvastatin
Timeframe: Group 2: Day 1 to Day 76
AUClast of rosuvastatin
Timeframe: Group 2: Day 1 to Day 76
Cmax of rosuvastatin
Timeframe: Group 2: Day 1 to Day 76
Ratio of Atorvastatin (Atorvastatin + elecoglipron) to Atorvastatin (alone) based on AUCinf (R AUCinf) of atorvastatin
Timeframe: Group 1: Day 1 to Day 71
Ratio of Atorvastatin (Atorvastatin + elecoglipron) to Atorvastatin (alone) based on AUClast (R AUClast) of atorvastatin
Timeframe: Group 1: Day 1 to Day 71
Ratio of Atorvastatin (Atorvastatin + elecoglipron) to Atorvastatin (alone) based on Cmax (R Cmax) of atorvastatin
Timeframe: Group 1: Day 1 to Day 71
Terminal elimination half-life (t1/2λz) of atorvastatin
Timeframe: Group 1: Day 1 to Day 71
Terminal rate constant (λz) of atorvastatin
Timeframe: Group 1: Day 1 to Day 71
Time to reach maximum observed concentration (tmax) of atorvastatin
Timeframe: Group 1: Day 1 to Day 71
Ratio of Rosuvastatin (Rosuvastatin + elecoglipron) to Rosuvastatin (alone) based on AUCinf (R AUCinf) of rosuvastatin
Timeframe: Group 2: Day 1 to Day 76
Ratio of Rosuvastatin (Rosuvastatin + elecoglipron) to Rosuvastatin (alone) based on AUClast (R AUClast) of rosuvastatin
Timeframe: Group 2: Day 1 to Day 76
Ratio of Rosuvastatin (Rosuvastatin + elecoglipron) to Rosuvastatin (alone) based on Cmax (R Cmax) of rosuvastatin
Timeframe: Group 2: Day 1 to Day 76
t1/2λz of rosuvastatin
Timeframe: Group 2: Day 1 to Day 76
λz of rosuvastatin
Timeframe: Group 2: Day 1 to Day 76
tmax of rosuvastatin
Timeframe: Group 2: Day 1 to Day 76