This study has three primary objectives to address the public health challenges of the Mpox outbreak in Guinea, West Africa. Objective 1 (MOVIE-West Africa) focuses on understanding the kinetics of Monkeypox virus (MPXV) elimination from the human body in Mpox cases. Objective 2 (TRACE-West Africa) aims to determine the MPXV transmission dynamics between Mpox cases and their contacts. Objective 3 (VE-West Africa) examines the vaccine effectiveness of the MVA-BN vaccine in protection against MPXV infection and Mpox disease.
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Viral clearance in oropharyngeal swabs
Timeframe: From day 1 to day 56
Secondary attack rate of infection
Timeframe: From day 1 to day 14
Secondary attack rate of disease
Timeframe: From day 1 to day 28