Targeted Lens Intervention for Myopic Anisometropia in Children (NCT07533149) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Targeted Lens Intervention for Myopic Anisometropia in Children
Singapore20 participantsStarted 2026-04
Plain-language summary
The goal of this clinical trial is to learn if our research spectacles will lower the difference in prescription (spectacles degree) between the eyes in children between 6 to 13 years old with anisometropic myopia. Anisometropic myopia is when the difference in myopia prescription between the two eyes are more than 1 diopter. The main question it aims to answer is:
* How the eye responds to the research spectacles over time by measuring:
1. Change in axial length: the physical length of the eye from front to back.
2. Change in cycloplegic spherical equivalent refraction: an accurate measurement of the eye's prescription taken while the focusing muscles are temporarily relaxed with eye drops.
Participants will:
* Wear the study spectacles
* Visit Essilor R\&D Centre and an eye clinic for follow-up sessions
Who can participate
Age range6 Years – 13 Years
SexALL
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Inclusion criteria
✓. Voluntary
✓. Informed consent of parent/guardian and assent of participant
✓. Age equal to or greater than 6 years old and less than 13 years at the time of signing informed consent and assent
✓. SER equal or less than -0.50 D and equal or greater than .5.00 D with astigmatism not more than 2.50 D
✓. Difference in SER (anisometropia) between two eyes .1.00 D
✓. Best corrected visual acuity (BCVA) better than or equal to +0.20 LogMAR in each eye
✓. Agree to wear study spectacles for .12 hours/day and 7 days/week
✓. Willingness and ability to participate in investigation for 12 months and attend scheduled visits punctually
Exclusion criteria
✕. History or presence of an ocular disease affecting refractive status
✕
What they're measuring
1
Change in axial length difference between the eyes
Timeframe: Base line, 12 months
2
Change in cycloplegic spherical equivalent refraction between the eyes