Targeted Lens Intervention for Myopic Anisometropia in Children (NCT07533149) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Targeted Lens Intervention for Myopic Anisometropia in Children
Singapore20 participantsStarted 2026-04
Plain-language summary
The goal of this clinical trial is to learn if our research spectacles will lower the difference in prescription (spectacles degree) between the eyes in children between 6 to 13 years old with anisometropic myopia. Anisometropic myopia is when the difference in myopia prescription between the two eyes are more than 1 diopter. The main question it aims to answer is:
* How the eye responds to the research spectacles over time by measuring:
1. Change in axial length: the physical length of the eye from front to back.
2. Change in cycloplegic spherical equivalent refraction: an accurate measurement of the eye's prescription taken while the focusing muscles are temporarily relaxed with eye drops.
Participants will:
* Wear the study spectacles
* Visit Essilor R\&D Centre and an eye clinic for follow-up sessions
Who can participate
Age range
6 Years – 13 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Voluntary
. Informed consent of parent/guardian and assent of participant
. Age equal to or greater than 6 years old and less than 13 years at the time of signing informed consent and assent
. SER equal or less than -0.50 D and equal or greater than .5.00 D with astigmatism not more than 2.50 D
. Difference in SER (anisometropia) between two eyes .1.00 D
. Best corrected visual acuity (BCVA) better than or equal to +0.20 LogMAR in each eye
. Agree to wear study spectacles for .12 hours/day and 7 days/week
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in axial length difference between the eyes
Timeframe: Base line, 12 months
2
Change in cycloplegic spherical equivalent refraction between the eyes