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Construction of a Clinico-Imaging Collaborative Diagnostic Model for Dermatomyositis Combined With Interstitial Lung Disease Based on PET/CT Imaging Features and Clinical Parameters

China200 participantsStarted 2026-01-13

Plain-language summary

The investigators investigated the associations between the imaging parameters of ⁶⁸Ga-FAPI and ¹⁸F-FDG dual-tracer PET/CT and concomitant interstitial lung disease (ILD) in patients with dermatomyositis (DM), developed a novel diagnostic model to predict DM complicated with ILD, and conducted external validation of this model. Meanwhile, the investigators compared the predictive performance of the imaging-only model with that of the classic clinical model and the clinical-radiological collaborative model.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. The diagnosis of dermatomyositis (DM) was made in accordance with the Bohan and Peter criteria
✓. The diagnosis of clinically amyopathic dermatomyositis (CADM) was established based on the Sontheimer criteria
✓. The diagnosis of interstitial lung disease (ILD) was confirmed in line with the criteria of the American Thoracic Society (ATS)
✓. ⁶⁸Ga-FAPI and ¹⁸F-FDG PET/CT scans were performed in the Department of Nuclear Medicine.

What they're measuring

Imaging features of 68Ga-FAPI PET image

Timeframe: baseline

Trial details

NCT IDNCT07531446

SponsorRuijin Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-01-01

View on ClinicalTrials.gov More Dermatomyositis (DM) trials