CompletedNot Applicable

The Effects of Dexamethasone and Ibuprofen on Postoperative Analgesia in Patients Undergoing Hand and Forearm Surgery With Axillary Brachial Plexus Block

Turkey (Türkiye)79 participantsStarted 2025-05-01

Plain-language summary

This study aims to comparatively examine the effects of preemptive intravenous dexamethasone and intravenous ibuprofen use on the duration of analgesia in ultrasound-guided Axillary Brachial Plexus Block applications for patients undergoing hand and forearm surgery. Furthermore, investigating the relationship between the study drugs and the incidence of Postoperative Nausea and Vomiting and determining the time until the first use of rescue analgesic are also among the secondary objectives.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient's consent to participate in the study (Informed consent) * Aged between 18 and 65 years * ASA physical status I or II * Being oriented and cooperative * Scheduled to undergo hand or forearm surgery * Body Mass Index (BMI) below 40 kg/m² * Scheduled for axillary brachial plexus blockade Exclusion Criteria: * Patient's refusal to participate in the study * Refusal of regional anesthesia * Known allergy to local anesthetics * Known allergy to ibuprofen * Known allergy to dexamethasone * Presence of coagulopathy * Local infection at the site of regional anesthesia application * Presence of malignancy at the surgical site * Diagnosis of diabetes mellitus * Body Mass Index (BMI) of 40 kg/m² or above * Duration of surgery exceeding 4 hours * Administration of opioid medication during the preoperative or intraoperative period

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Duration of analgesia

Timeframe: 24 hours

Trial details

NCT IDNCT07531407

SponsorProf. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-10-31

View on ClinicalTrials.gov More Axillary Block trials