HUMSCs Combined With Col I to Third-Degree Burn Wound (NCT07530003) | Clinical Trial Compass
RecruitingPhase 1/2
HUMSCs Combined With Col I to Third-Degree Burn Wound
China108 participantsStarted 2026-04-06
Plain-language summary
To evaluate the safety and tolerability of human umbilical cord mesenchymal stem cells combined with bovine type I collagen in the treatment of third-degree burn wounds.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18-65 years, gender unrestricted
* Confirmed third-degree burns, wound area 1%-5% TBSA
* Admission within 72 hours after burn injury
* Voluntarily signed informed consent
* Able to cooperate and complete follow-up
Exclusion Criteria:
* Pregnant or lactating females
* Severe immunodeficiency or autoimmune disease
* History of malignant tumor, or coagulation dysfunction
* Severe cardiac, hepatic, or renal insufficiency
* Hypersensitivity to collagen or stem cell components
* Uncontrollable severe wound infection
* Participation in other clinical studies within the past 3 months
* Inability to comply with follow-up
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Re-epithelialization areas
Timeframe: Up to 6 month
2
Complete burn wound healing
Timeframe: Up to 12 month
Trial details
NCT IDNCT07530003
SponsorThe First Affiliated Hospital of Xinxiang Medical College