RecruitingNot Applicable

A Study Of Exercise In Patients With Spontaneous Coronary Artery Dissection And Fibromuscular Dysplasia

United States28 participantsStarted 2026-04-01

Plain-language summary

The purpose of this study is to assess the cardiopulmonary, hemodynamic, and symptom responses to acute bouts of varying intensity aerobic and resistance exercise in people with Spontaneous Coronary Artery Dissection (SCAD) and/or Fibromuscular Dysplasia (FMD).

Who can participate

Age range21 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria: * History of Spontaneous Coronary Artery Dissection (SCAD) and/or Fibromuscular Dysplasia (FMD), ≥2 months post-event, and free from chest pain. * Able to provide written informed consent Exclusion criteria: * Individuals who are clinically obese (BMI ≥36) and/or who suffer from musculoskeletal or other conditions that would limit exercise participation. * Individuals who are deemed medically unstable * Participants who are unable to comply with study requirements. * Pregnancy

What they're measuring

Change in blood pressure in response to aerobic exercise

Timeframe: Baseline, 5 minutes, 25 minutes, 50 minutes and 55 minutes

Dartmouth COOP Functional Assessment Chart score

Timeframe: Baseline

Duke Activity Index Status (DASI) score

Timeframe: Baseline

International Physical Activity Questionnaire Short Form (IPAQ-SF) score

Timeframe: Baseline

Change in perceived exertion

Timeframe: Baseline, 25 minutes, and 50 minutes

Change in blood lactate concentration [La-]b

Timeframe: Baseline, 25 minutes, and 50 minutes

Trial details

NCT IDNCT07526766

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-04-30

Contact for this trial

Armia R. Habil, MD

904-953-0859 habil.armia@mayo.edu

View on ClinicalTrials.gov More Fibromuscular Dysplasia trials