RecruitingNot Applicable

Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery

Turkey (Türkiye)60 participantsStarted 2026-04-15

Plain-language summary

Laparoscopic surgeries require pneumoperitoneum and Trendelenburg position, which may lead to increased intracranial pressure (ICP). Optic nerve sheath diameter (ONSD) measurement via ultrasound is a non-invasive method to evaluate ICP. This prospective study aims to compare the effects of sevoflurane and desflurane on ONSD in patients undergoing laparoscopic hysterectomy and bilateral oophorectomy in the Trendelenburg position.

Who can participate

Age range18 Years – 85 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients planned for laparoscopic hysterectomy bilateral oophorectomy surgery under general anesthesia. Exclusion Criteria: * Patients receiving beta-blocker or diuretic treatment. * Patients with severe heart failure. * Patients diagnosed with diabetes with ocular or neurological complications. * Patients who have undergone cardiac surgery, eye surgery, brain surgery, or thoracic surgery. * Patients with a history of hydrocephalus, glaucoma, intracranial mass, and stroke.

What they're measuring

Optic Nerve Sheath Diameter (ONSD)

Timeframe: Intraoperative (approx. 2-4 hours): immediately and 10 min post-intubation, 10 and 60 min post-Trendelenburg/pneumoperitoneum, 10 min post-neutral position."

Trial details

NCT IDNCT07525648

SponsorMedipol University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05-10

View on ClinicalTrials.gov More Intracranial Pressure trials