The Effect of Proprioceptive Neuromuscular Facilitation on Haemodynamic Responses in a Neurologic… (NCT07524790) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The Effect of Proprioceptive Neuromuscular Facilitation on Haemodynamic Responses in a Neurological Intensive Care
24 participantsStarted 2026-05-15
Plain-language summary
Although there are studies examining the effect of actively performed PNF exercises on haemodynamic responses in intensive care patients and healthy individuals, there are no studies investigating their effect on circulation and haemodynamic responses in unconscious patients. Therefore, this study was designed to investigate the acute effects of proprioceptive neuromuscular facilitation (PNF) exercises on peripheral circulation and haemodynamic responses in patients admitted to a neurological intensive care unit.
Hypotheses:
H1-1: Passively administered PNF exercises have beneficial effects on peripheral circulation.
H2-1: Passively administered PNF exercises have beneficial effects on haemodynamic responses.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients being monitored in the neurology intensive care unit
* Aged 18 years or over
* Haemodynamically stable
* No orthopaedic condition preventing the performance of passive joint movements in the upper and lower limbs
* A signed informed consent form from a patient's next of relative for participation in the study
Exclusion Criteria:
* Presence of haemodynamic instability
* Fractures, contractures or serious orthopaedic conditions in the upper or lower limbs that restrict movement
* Diagnosis or suspicion of deep vein thrombosis
* Severe peripheral arterial disease
* Serious cardiac arrhythmia that may prevent exercise
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Ankle-Brachial İndex
Timeframe: Baseline and five or ten minutes after exercise
2
Heart Rate
Timeframe: Baseline and five or ten minutes after exercise
3
Systolic blood pressure and diastolic blood pressure
Timeframe: Baseline and five or ten minutes after exercise
4
Respiratory rate
Timeframe: Baseline and five or ten minutes after exercise
5
Peripheral oxygen saturation (SpO₂)
Timeframe: Baseline and five or ten minutes after exercise