RecruitingNot Applicable

Intrathecal Dexmedetomidine With Bupivacaine, in Patients Undergoing Knee Orthopedic Surgery

Egypt120 participantsStarted 2025-03-01

Plain-language summary

This study aims to compare the duration of analgesia (as the primary outcome) and adverse effects (as the secondary outcome) after intrathecal administration of dexmedetomidine with hyperbaric bupivacaine to patients undergoing knee orthopedic surgery.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age from 18 to 65 years. * American Society of Anesthesiologists (ASA) physical status I-II. * Male patients scheduled for knee orthopedic surgery. Exclusion Criteria: * Patients with psychiatric disorders. * History of drug addiction. * Contraindication for regional anesthesia. * History of hypersensitivity to the study drugs. * Previous administration of opioids and/or other central nervous system depressants during current hospital admission.

What they're measuring

Time to request rescue analgesia

Timeframe: 24 hours postoperatively

Trial details

NCT IDNCT07522736

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08-30

Contact for this trial

Ahmed A Ismail, MSc

00201115746779 ahmed.ali39348@postgrad.kasralainy.edu.eg

View on ClinicalTrials.gov More Intrathecal Dexmedetomidine trials