Not Yet RecruitingNot Applicable

Exercise Training in Women With Metastatic Breast Cancer

Brazil78 participantsStarted 2026-04

Plain-language summary

The primary objective of the study is to evaluate the effects of exercise on physical function, physical fitness, and body composition, with the main components including muscular strength, cardiorespiratory fitness, muscle mass, fat mass, and fat-free mass. The secondary objectives are to examine exercise adherence and the effects of exercise on health-related quality of life (HRQoL), cancer-related fatigue, and sleep quality. Additionally, the feasibility and safety of the exercise program will be assessed.

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women aged ≥ 18 years; * Confirmed diagnosis of stage IV (metastatic) breast cancer; * Currently undergoing medical treatment; * Willingness and functional independence to participate in the exercise program; * Medical clearance to engage in structured physical exercise. Exclusion Criteria: * Presence of unstable bone metastases. * Untreated or symptomatic brain metastases; * Evidence of severe cardiovascular disease identified by electrocardiogram (ECG); * Severe active infection; * Uncontrolled severe respiratory insufficiency or dependence on supplemental oxygen at rest or during exercise; * Uncontrolled severe pain; * Any other medical condition contraindicating participation in physical exercise; * Conditions that impair adherence to study procedures or the ability to provide informed consent; * Pregnancy.

What they're measuring

Cardiorespiratory endurance and functional capacity

Timeframe: Baseline and week 24 (post exercise intervention)

Lower-limb muscle strength

Timeframe: Baseline and week 24 (post exercise intervention)

Handgrip strength

Timeframe: Baseline and week 24 (post exercise intervention)

Trial details

NCT IDNCT07521826

SponsorState University of Londrina

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-04

Contact for this trial

Rafael Deminice, PhD

+5543991916013 rdeminice@uel.br

View on ClinicalTrials.gov More Cancer trials

Plain-language summary

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.