Exercise Training in Women With Metastatic Breast Cancer (NCT07521826) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Exercise Training in Women With Metastatic Breast Cancer
Brazil78 participantsStarted 2026-04
Plain-language summary
The primary objective of the study is to evaluate the effects of exercise on physical function, physical fitness, and body composition, with the main components including muscular strength, cardiorespiratory fitness, muscle mass, fat mass, and fat-free mass. The secondary objectives are to examine exercise adherence and the effects of exercise on health-related quality of life (HRQoL), cancer-related fatigue, and sleep quality. Additionally, the feasibility and safety of the exercise program will be assessed.
Who can participate
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Women aged ≥ 18 years;
* Confirmed diagnosis of stage IV (metastatic) breast cancer;
* Currently undergoing medical treatment;
* Willingness and functional independence to participate in the exercise program;
* Medical clearance to engage in structured physical exercise.
Exclusion Criteria:
* Presence of unstable bone metastases.
* Untreated or symptomatic brain metastases;
* Evidence of severe cardiovascular disease identified by electrocardiogram (ECG);
* Severe active infection;
* Uncontrolled severe respiratory insufficiency or dependence on supplemental oxygen at rest or during exercise;
* Uncontrolled severe pain;
* Any other medical condition contraindicating participation in physical exercise;
* Conditions that impair adherence to study procedures or the ability to provide informed consent;
* Pregnancy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Cardiorespiratory endurance and functional capacity
Timeframe: Baseline and week 24 (post exercise intervention)
2
Lower-limb muscle strength
Timeframe: Baseline and week 24 (post exercise intervention)
3
Handgrip strength
Timeframe: Baseline and week 24 (post exercise intervention)