Integrated Rehabilitation in HDU for Post-Intensive Care SyndromeLiberation in Patients With PICS (NCT07521540) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Integrated Rehabilitation in HDU for Post-Intensive Care SyndromeLiberation in Patients With PICS
China250 participantsStarted 2026-04-01
Plain-language summary
Post-intensive care syndrome (PICS) is characterized by persistent physical, cognitive, and psychological impairments among survivors of critical illness. Although advances in intensive care medicine have reduced mortality, a large proportion of ICU survivors experience long-term functional impairments after discharge.
High-dependency units (HDUs) serve as transitional care settings between intensive care units and general wards. Many critically ill survivors who cannot directly return home are transferred to HDU for continued treatment and rehabilitation. However, evidence regarding systematic multidisciplinary rehabilitation interventions in HDU settings remains limited.
This prospective single-center interventional study aims to evaluate the effects of an integrated multidisciplinary rehabilitation model implemented in the HDU on physical, cognitive, and psychological outcomes among patients with post-intensive care syndrome. All enrolled patients will receive standardized integrated medical, nursing, and rehabilitation interventions. Multidimensional functional assessments will be conducted at baseline, during hospitalization, and before discharge from the HDU.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥18 years
* Diagnosed with post-intensive care syndrome
* Transferred from ICU to HDU
* Available paired admission and discharge data
Exclusion Criteria:
* Death within 24 hours after HDU admission
* Missing primary outcome data
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1My loved one spent time in the ICU and is now recovering — could you explain what Post-Intensive Care Syndrome actually is, and whether their current symptoms suggest this trial's rehabilitation program might be worth discussing?
2This trial is listed as 'not yet recruiting' — do you know when it's expected to open, and is there any risk that waiting to see if we qualify could affect their recovery window?
3The trial is measuring physical function using something called a CPAx score — can you explain what that measures, and how their current physical condition compares to the kind of patients this study seems to be designed for?
4Since this trial takes place in a High Dependency Unit setting, what would that mean practically for our family in terms of where care happens, how long they'd need to stay, and what level of participation would be expected from them day to day?
5Before considering a trial like this, are there standard rehabilitation programs already available for ICU recovery that we should try first, or would entering a study like this actually give access to more structured support than they'd get otherwise?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Physical Function (CPAx Score)
Timeframe: Baseline (within 48 hours after HDU admission) and at HDU discharge，assessed up to 2 days