Silver compounds have demonstrated a positive effect in most medical fields, including periodontal therapy, particularly in their nano-formulations. These nanoparticles have exhibited a significant capacity to accelerate healing and possess antibacterial and anti-inflammatory properties, in addition to their ability to mitigate pain and postoperative complications.
Who can participate
Age range20 Years – 40 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Gingival Hyperpigmentation: Presence of physiological melanin pigmentation in the maxillary anterior region, categorized as Grade 3 or 4 according to the Heden Gingival Pigmentation Index.
✓. Age Demographic: Patients aged 20 years or older.
✓. Periodontal Health: Absence of active periodontal disease (e.g., periodontitis or gingivitis).
✓. Gingival Biotype: Presence of a medium-to-thick gingival biotype.
✓. Attached Gingiva: An adequate width of attached gingiva to ensure surgical stability.
✓. Oral Hygiene: Demonstration of good oral hygiene with a proven ability to maintain effective plaque control throughout the study period.
Exclusion criteria
✕. Systemic Pigmentation: Presence of gingival discoloration secondary to systemic conditions or metabolic disorders.
✕. Drug-Induced Pigmentation: Hyperpigmentation resulting from the administration of specific pharmacological agents.
✕. Poor Oral Hygiene: Inadequate plaque control or a lack of compliance with oral self-care instructions.
✕. Smoking Status: Current smokers or individuals with a recent history of tobacco use, due to its confounding effect on gingival pigmentation and wound healing.
✕. Physiological Status: Pregnant or lactating women.
What they're measuring
1
Wound Healing: Clinical Tissue Healing Index
Timeframe: Measured weekly, one week postoperatively until week 4 (measured 4 times).
2
Epithelization: Clinical epithelialization Index
Timeframe: Measured weekly, one week postoperatively until week 4 (measured 4 times).
. Systemic Health \& Medication: Patients with underlying systemic diseases or those receiving medications known to influence periodontal tissue integrity or inflammatory response (e.g., immunosuppressants or calcium channel blockers).
✕. Periodontal Disease: Presence of active periodontitis or attachment loss.