CompletedNot Applicable

Gingival Depigmentation With Diode and Er,Cr:YSGG Laser: A Split-mouth Trial

Vietnam38 participantsStarted 2023-03-01

Plain-language summary

Gingival hyperpigmentation is a common physiological condition caused by excessive melanin deposition in oral mucosa, negatively affecting smile esthetics. Laser therapy has become an effective treatment option due to advantages such as minimal bleeding, reduced postoperative discomfort, and faster healing. This clinical study aims to evaluate clinical characteristics of gingival pigmentation and compare treatment outcomes between diode laser and Er,Cr:YSGG laser techniques. Outcomes include pigmentation reduction, postoperative pain, wound healing, bleeding, patient satisfaction, and recurrence rate.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * all patients exhibiting physiological melanin hyperpigmentation of score 1 or more according to the oral pigmentation index (DOPI) in the buccal maxillary gingiva Exclusion Criteria: * history of systemic diseases related to pathology * participants with a systemic condition that could affect tissue healing (e.g., uncontrolled diabetes, autoimmune diseases, HIV, leukemia, etc.) * pregnancy and lactation * a history of smoking; previously used drugs (related to pigmentation) before the intervention within the last 6 months * contraindication for laser treatment.

What they're measuring

Change in gingival pigmentation measured by Dummett-Gupta Oral Pigmentation Index (DOPI)

Timeframe: Baseline, 7 days, 1 month, 3 months

Change in gingival pigmentation measured by Melanin Pigmentation Index (MPI)

Timeframe: Baseline, 7 days, 1 month, 3 months

Trial details

NCT IDNCT07520266

SponsorCan Tho University of Medicine and Pharmacy

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-05-01