The goal of this study is to learn about the effects of sacral neuromodulation in pediatric patients with gastrointestinal motility disorders. By combining advanced neuroimaging, patient-specific biophysical modeling, electrophysiological characterization, and clinical translation, the SMART-GUT project establishes a comprehensive framework to systematically investigate neuromodulation in this pediatric population. This integrative approach enables a direct link between mechanism, targeting, and clinical outcome.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Fecal incontinence
Timeframe: Within 12 weeks of sacral neuromodulation
Abdominal pain
Timeframe: Within 12 weeks of sacral neuromodulation
Defecation frequency
Timeframe: Within 12 weeks of sacral neuromodulation
Urinary incontinence
Timeframe: Within 12 weeks of sacral neuromodulation
Proprioception
Timeframe: Within 12 weeks of sacral neuromodulation