Active — Not RecruitingNot Applicable

Acute Effect of Polyphenols Supplementation on Endothelial Function and Exercise Related Markers, in Physically Active Healthy Volunteers.

France38 participantsStarted 2025-09-01

Plain-language summary

To evaluate the effect of acute polyphenols supplementation on vasodilation and related markers along with exercise related markers (notably performance, respiratory exchanges, perceived exertion), before, during and after a hypoxic moderate-intensity exercise in healthy recreative volunteers.

Who can participate

Age range35 Years – 55 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * BMI \< 27 * Abdominal circumference \< 94 cm * Stable exercise training program during past 2 months Exclusion Criteria: * Total weekly exercise sessions \< 4 hours OR \> 8 hours * Drug or supplement intake during past one month that could interfere with study parameters * Volunteer suffering of respiratory or pulmonary condition * Volunteer exposed to an altitude \> 2000 meters during at least 3 weeks for the past 6 months.

What they're measuring

Flow mediated dilation (FMD ; %)

Timeframe: Before the exercise session (at rest under normoxia and hypoxia conditions)

Trial details

NCT IDNCT07518758

SponsorNexira

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2026-04-20

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