Hypnosis During Mechanical Ventilation Weaning (NCT07518498) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Hypnosis During Mechanical Ventilation Weaning
France30 participantsStarted 2026-07-01
Plain-language summary
Hypnosis is defined as an altered state of consciousness characterized by an increased susceptibility to suggestion. It is a technique commonly used in the medical field, primarily for the management of pain and anxiety.
The literature demonstrates that better pain management is correlated with a shorter length of stay in the ICU and a shorter duration of mechanical ventilation.
In patients hospitalized in the ICU requiring invasive mechanical ventilation, the emotional component plays a significant role in dyspnea, which can become an obstacle to weaning from ventilation. The analgesic and anxiolytic treatments used carry numerous side effects and contraindications, limiting their use in ICU patients. Furthermore, pulmonary edema is a common cause of failure to wean from invasive mechanical ventilation. By reducing the occurrence of hypertension and tachycardia, hypnosis could be used as a therapeutic strategy to limit its incidence. Thus, hypnosis could be a valuable therapeutic tool for improving tolerance and the success of ventilator weaning.
Although hypnosis is already commonly used in intensive care units, its use is still limited by a lack of evidence for more specific indications. It is in this context that this study was conducted, to assess the feasibility of conducting a hypnosis session during weaning from invasive mechanical ventilation in the intensive care unit.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients aged 18 and older
* Patients hospitalized in the intensive care unit and requiring invasive mechanical ventilation for at least 48 hours
* Presence of the prerequisite criteria for ventilator weaning: effective cough, minimal bronchial congestion, patient awake and not agitated, hemodynamic stability (heart rate less than 140 beats per minute, systolic blood pressure between 90 and 160 mmHg without vasopressors), pressure support ventilation, FiO2 \< 40% and PEEP ≤ 8 cmH2O, PaO2/FiO2 \> 150, pH \> 7.35, respiratory rate \< 35 per minute
* Patients enrolled in a social security program or eligible for such a program
* Patients who has received complete information about the clinical research protocol and has signed an informed consent form
* Patients who has undergone a preliminary clinical examination appropriate for the clinical research
Exclusion Criteria:
* Contraindication to hypnosis (particularly severe psychotic disorders)
* Non-French-speaking individuals
* Deaf or hard-of-hearing individuals
* State of agitation or acute delirium
* Individuals who have already undergone a spontaneous ventilation test or an attempt at orotracheal extubation during their hospitalization
* Individuals receiving a new anxiolytic or sedative treatment within 2 hours prior to the weaning test
* Individuals with a tracheostomy
* Women of childbearing age who do not have access to effective contraception
* Individuals covered by Articles L. 1121-5, L. 1121-7…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Feasibility of a hypnosis session during weaning from invasive mechanical ventilation.