RecruitingNot Applicable

Dietary Insights and Nutritional Education in Adults on GLP-1 Therapy

United States50 participantsStarted 2026-04-06

Plain-language summary

This pilot study will evaluate the feasibility, acceptability, and perceived usefulness of the SWITCH mobile nutrition behavioral intervention among adults receiving GLP-1 receptor agonist therapy for obesity and/or type 2 diabetes. Participants will complete baseline assessments, receive a 6-week app-based nutrition intervention consisting of daily dietary self-monitoring and weekly learning modules, and complete follow-up assessments and a structured interview.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * • Age between 18 and 65 years. * BMI between 30 - 49.9 kg/m2 and/or diagnosed with type 2 diabetes. * Currently prescribed and using GLP-1 receptor therapy for at least 4 weeks. * Own a smartphone (Android or iOS) with an active data plan to support app-based intervention delivery. * Residing anywhere in the United States. * Must be willing and able to reduce caloric intake. * Be free of major health or psychiatric diseases, drug, or alcohol dependency. * Willing to sign informed consent. Exclusion Criteria: * • Presence of type 1 diabetes mellitus * Severe complications, including but not limited to proliferative retinopathy, severe peripheral neuropathy, nephropathy requiring dialysis, active foot ulcers, or recent hospitalization for diabetic ketoacidosis or hyperosmolar hyperglycemic state within the past 6 months. * Current or recent (within 6 months) participation in another structured weight loss program or clinical trial that may interfere with study outcomes. * Pregnancy, breastfeeding, or plans to become pregnant during the study period. * Current use of another investigational weight loss device or medication. * Diagnosed eating disorders (e.g., anorexia nervosa, bulimia nervosa, binge eating disorder) or other psychiatric conditions that may affect adherence to behavioral interventions, as determined by study staff. * Severe cardiovascular, hepatic, renal, or pulmonary disease that would limit participation in m…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1This trial is testing a dietary education program for people already on GLP-1 therapy — does my current GLP-1 medication and diabetes or weight management situation make this kind of nutritional support something worth adding right now?
2Since this study is listed as 'Phase NA' and is focused on measuring how acceptable and easy to use the educational program is rather than testing a drug's safety or effectiveness, what does that mean for what I'd actually be learning or doing if I joined?
3The trial is measuring things like 'usefulness' and 'ease of use' of the intervention — can you help me understand what the program actually involves day-to-day, and whether the time and effort commitment would realistically fit into my life?
4Given that this study is still in an early stage of evaluating the program itself, would I be better served by standard dietitian or nutrition counseling first, or could participating in this trial serve a similar purpose alongside my existing treatment?
5If I enrolled and found the dietary education program wasn't working for me, would I still be able to continue my GLP-1 medication and access other nutritional support outside the trial?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Intervention acceptability, usefulness and ease of use

Timeframe: End of 6-week intervention

Trial details

NCT IDNCT07518407

SponsorUniversity of South Carolina

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-04-01

Contact for this trial

Shiba Bailey

8035765688 SB25@email.sc.edu

View on ClinicalTrials.gov More Obesity Type 2 Diabetes Mellitus trials