Not Yet RecruitingNot Applicable

Bilogical Assesment During Intrusion of Lower Incisors

16 participantsStarted 2026-04

Plain-language summary

biological assesment during intrusion of lower incisors

Who can participate

Age range14 Years – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients requiring extraction-based orthodontic treatment * Presence of deep overbite requiring lower incisor intrusion * Age range: 18-30 years * Good general health * Good oral hygiene Exclusion Criteria: * Systemic diseases affecting bone metabolism * Previous orthodontic treatment * Periodontal disease * Smoking * Pregnancy or lactation

What they're measuring

Gingival crevicular fluid (GCF) prostaglandin E2 (PGE2) levels measured by enzyme-linked immunosorbent assay (ELISA) (pg/mL)

Timeframe: 12 weeks

Trial details

NCT IDNCT07514403

SponsorAl-Azhar University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-05

Contact for this trial

alaa eldin elshahat shafay, post gradute student

+201016886788 alaaelshafay9@gmail.com

View on ClinicalTrials.gov More Orthodontic Treatment Efficiency trials