Proof of Concept Study Evaluating the Efficacy and Safety of ATH-063 Treatment in Patients With Relapsed/Refractory Moderately to Severely Active Ulcerative Colitis (UC)

Inclusion criteria

• ✓. Hemoglobin ≥8 g/dL
• ✓. White blood cell (WBC) ≥3×103/μL
• ✓. Neutrophil count ≥1.5×103/μL
• ✓. Platelet count ≥100,000/μL
• ✓. Serum creatinine ≤1.5 mg/dL and/or creatinine clearance \>80 mL/min
• ✓. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) values must be within 2× the upper limit of normal (ULN) for the laboratory conducting the test
• ✓. Total bilirubin ≤1.5×ULN at screening in participants who do not have Gilbert's syndrome
• ✓. Total bilirubin ≤2×ULN at screening in participants with Gilbert's syndrome