Tetanus Severity Score for Prediction of Mortality in Manifest Tetanus (NCT07512167) | Clinical Trial Compass
RecruitingNot Applicable
Tetanus Severity Score for Prediction of Mortality in Manifest Tetanus
Egypt115 participantsStarted 2025-06-15
Plain-language summary
Three scoring systems will be applied to patients suffering from manifest tetanus and will be related to mortality.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria:
* Adults (age 18 years old or more).
* Any sex (male or female), regardless of gender identity.
* Diagnosis of manifest tetanus according to the WHO criteria (https://www.who.int/news-room/fact-sheets/detail/tetanus), that is the presence of one or both of the following criteria with or without the history of specific wound or injury:
* Sustained spasm of the facial muscles in which person appears grinning.
* Painful muscular contractions
Exclusion criteria:
* Age \< 18 years.
* Absent criteria of manifest tetanus, as per the WHO criteria (https://www.who.int/news-room/fact-sheets/detail/tetanus).
* Incomplete medical record with missing data required to calculate the Tetanus Severity Score, Philips Score, or Dakar score.
* Incomplete medical record with missing data regarding the primary outcome measure (survival to hospital discharge or in-hospital mortality).
What they're measuring
1
Death from any cause.
Timeframe: From the date of onset of symptoms until the date of death or date of discharge from the hospital, whichever comes first, assessed up to 90 days.