Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses (NCT07510620) | Clinical Trial Compass
RecruitingPhase 4
Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses
United States30 participantsStarted 2025-12-12
Plain-language summary
This research study is to see if using Lacrifill is safe, easy to use, and helpful for people who wear contact lenses but can't wear them comfortably for long. Specifically, the study aims to determine whether regular use of Lacrifill over a 2-3 month period can help people wear their contacts longer without discomfort and reduce signs and symptoms of dry eye.
Who can participate
Age range
22 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria
* \>21 years of age
* Contact lens wearer
* Previous Dry Eye Treatment
* Be on a stable dose of antihistamines/Birth Control Medication and Lifitegrast and cyclosporine.
* Schrimers Anesthetized less than or equal to 10
* CLDEQ-8 greater than or equal to 12
* Corneal Staining NEI grading scale greater than or equal to 1
Exclusion Criteria:
* Known allergy to Hyaluronic Acid
* Current topical ophthalmic drops other than dry eye treatment
* Uncontrolled Diabetes
* Diabetic Retinopathy
* Pregnancy or Lactating
* Corneal Surgery (except Refractive)
* Corneal Scars
* Keratoconus
* Ocular Herpetic Keratitis
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Dry eye signs
Timeframe: 2-3 months
2
Dry Eye Symptoms
Timeframe: 2-3 Months
3
Contact Lens Tolerability
Timeframe: 2-3 Months
Trial details
NCT IDNCT07510620
SponsorVision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists