CompletedNot Applicable

Transcranial Alternating Current Stimulation in Post Stroke Aphasia Therapy

Poland11 participantsStarted 2019-12-01

Plain-language summary

This study aims to investigate the efficacy of transcranial alternating current stimulation (tACS) combined with linguistic training for patients with chronic post-stroke aphasia. Thirteen patients will participate in a randomized crossover clinical trial. Their naming ability will be assessed before and after two-weeks of therapy (with 16 days of washout) supported by either 75Hz tACS or sham stimulation. The stimulated cortical area will be selected individually based on the results of functional magnetic resonance imaging.

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * presence of aphasia (Broca's or mixed) * first ever stroke with one major lesion in left hemisphere * chronic stage (at least 6 months since onset) * right handedness * capability to give an informed consent * Native Polish speaker * 5-80% correct responses in the first naming task Exclusion Criteria: * history of neurosurgical interventions * history of other neurological or psychiatric conditions (including dementia, head trauma, alcohol abuse etc.) * reports of seizures during last 36 months * serious vision disorders * medications increasing risk of seizures or influencing neuroplasticity * electrically, magnetically or mechanically activated implants or other systems sensitive to electricity in the body * history of language and/or speech disorders or intellectual disability in childhood * bilingualism * pregnancy * claustrophobia

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Percentage accuracy in a picture-naming task (trained items)

Timeframe: Assessed immediately after completion of the intervention (last session), at 2-week, and 6-week follow-up

Trial details

NCT IDNCT07510464

SponsorQVITI S.A.

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2021-12-30

View on ClinicalTrials.gov More Stroke trials