Whole-Body Vibration on Balance, Risk of Falling and Quality of Life in Chemotherapy-Induced Peri… (NCT07508527) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Whole-Body Vibration on Balance, Risk of Falling and Quality of Life in Chemotherapy-Induced Peripheral Neuropathy
30 participantsStarted 2026-04
Plain-language summary
The goal of this clinical trial is to evaluate the efficacy of Whole-body vibration in improving postural control, risk of falling, and quality of life in patients with chemotherapy-induced peripheral neuropathy. The main questions it aims to answer are:
Does Whole-body vibration have a significant effect on postural control, risk of falling, and quality of life in patients with chemotherapy-induced peripheral neuropathy?
Researchers will compare whole body vibration in addition to traditional exercise to traditional exercise alone to see if Whole-body vibration have a significant effect on postural control, risk of falling, and quality of life in patients with chemotherapy-induced peripheral neuropathy.
Participants will:
* age between 30-60 years old.
* be on chemotherapy for at least one cycle as a treatment of malignant tumors with peripheral neuropathy.
* have mild to moderate neuropathy according to mTNS.
* be assigned randomly into two equal groups (control group (A) and study group (B)).
* Take three sessions per week for eight weeks.
* The control group (A) will be treated by selected physical therapy treatment (Strength resistive training, Stretching \& flexibility, Balance training)
* The study group (B) will be treated with selected physical therapy treatment in addition to whole-body vibration therapy.
Who can participate
Age range
30 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 30 patients diagnosed with chemotherapy-induced peripheral neuropathy from both genders.
* Their ages will range from 30-60 years old.
* All patients included in this study will be on chemotherapy from at least one cycle as a treatment of malignant tumor.
* The patients will be mild to moderate neuropathy according to mTNS.
* They were medically stable.
Exclusion Criteria:
* History of other types of neuropathies (i.e., hereditry peripheral neuropathy associated with nutritional agents and paraneoplastic syndrome-related neuropathy…etc).
* Unstable medical condition during chemotherapy
* Patients who are starting new therapy or dose modification during study period
* Morbid obesity body mass index \>40%
* History of non-surgically repaired nerve compression injuries such as carpal tunnel, brachial plexopathy, spinal stenosis, and spinal nerve root compression
* History of central nervous system primary or metastatic malignancy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Risk of fall
Timeframe: From enrollment to the end of treatment at 8 weeks
2
Quality of life (QOL)
Timeframe: From enrollment to the end of treatment at 8 weeks
3
Balance
Timeframe: From enrollment to the end of treatment at 8 weeks