Effects of Exercise in Hemodialysis (NCT07507981) | Clinical Trial Compass
CompletedNot Applicable
Effects of Exercise in Hemodialysis
Mexico18 participantsStarted 2025-05-01
Plain-language summary
Objective: To evaluate the effects of a six-month intradialytic aerobic exercise program on left ventricular ejection fraction in patients with end-stage kidney disease undergoing maintenance hemodialysis.
Materials and Methods Design: Open-label, single-center, quasi-experimental, single-group study with pre- and post-intervention measurements.
Study setting: the outpatient hemodialysis unit of the National Institute of Medical Sciences and Nutrition Salvador Zubirán.
Participants: Patients aged ≥18 years with chronic kidney disease on hemodialysis for at least three months, who are at their dry weight.
Procedures: An echocardiogram will be performed post-hemodialysis. Subsequently, patients will undergo a 30-minute intradialytic aerobic exercise program at submaximal intensity during the second hour of dialysis, three times per week for six months. At the end of the six-month period, a post-hemodialysis echocardiogram will be repeated.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged ≥18 years
* Receiving hemodialysis with a stable prescription for at least 3 months
* At their prescribed dry weight
* Provision of written informed consent
Exclusion Criteria:
* Active cardiovascular disease within the past 3 months
* Left ventricular ejection fraction \<40%
* Physical and/or cognitive impairment precluding exercise
* Blood pressure \>160/110 mmHg
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial looked at how exercise during hemodialysis affects left ventricular ejection fraction — since ejection fraction measures how well the heart pumps, would my current heart function make this kind of exercise program appropriate or risky for me?
2The trial is listed as completed — has the data been published yet, and if so, what did it show about whether exercise during dialysis sessions actually improved heart pumping function?
3Since this was a phase 'not applicable' study, what does that mean for how confident we can be in the safety and effectiveness of exercise during hemodialysis based on this research?
4Would adding an exercise program during my hemodialysis sessions be something my care team could support and monitor, or are there reasons specific to my condition that would make this difficult to do safely?
5Are there standard care approaches already recommended for protecting heart function in hemodialysis patients that I should consider before looking into exercise programs like the one studied in this trial?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Left ventricular ejection fraction
Timeframe: From study enrollment to the initiation of the exercise program (within a maximum of 6 weeks), and subsequently from completion of the exercise program to up to 6 weeks thereafter
Trial details
NCT IDNCT07507981
SponsorInstituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran