Relationship Between RAR and MACEs in AMI-CS Patients During Hospitalization (NCT07507110) | Clinical Trial Compass
CompletedNot Applicable
Relationship Between RAR and MACEs in AMI-CS Patients During Hospitalization
China264 participantsStarted 2019-07-01
Plain-language summary
This is a retrospective study from double center: Xuzhou Central Hospital and The First People's Hospital of Yancheng. Acute myocardial infarction (AMI) were screened and AMI complicating with cardiogenic shock were included. This study is to investigate the relationship between red blood cell distribution width-to-albumin ratio (RAR) and major adverse cardiovascular events (MACEs) in acute myocardial infarction complicated with cardiogenic shock (AMI-CS) patients during hospitalization.
Who can participate
Age range18 Years – 90 Years
SexALL
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Inclusion criteria
✓. Age over 18 years and under 90 years;
✓. Meeting the diagnostic criteria for acute myocardial infarction: myocardial injury markers (preferably troponin) ≥ 99th percentile of the upper limit of normal value, combined with at least one evidence of myocardial ischemia: persistent myocardial ischemic symptoms ≥ 30 minutes; accompanied by ST-segment elevation or depression on electrocardiogram;
✓. Meeting the diagnostic criteria for cardiogenic shock: systolic blood pressure \< 90 mmHg, accompanied by clinical symptoms of pulmonary congestion such as dyspnea, and at least one of the following peripheral organ perfusion impairments: altered mental status; cold and clammy skin; urine output \< 30 ml/h; or serum lactate level \> 2.0 mmol/L.
Exclusion criteria
✕. Coexisting cerebrovascular disease, peripheral vascular disease or embolic disease;
✕. Myocardial infarction caused by coronary artery embolism or blood flow interruption due to peripheral embolus detachment or invasive diagnostic and therapeutic procedures;
✕. History of surgery, trauma or infection within one month;
✕
What they're measuring
1
the occurrence of major adverse cardiovascular events (MACEs) during hospitalization.
. History of severe liver or kidney dysfunction, , including alanine aminotransferase (ALT), aspartate aminotransferase (AST), and γ-glutamyl transpeptidase (γ-GGT) \> 2.5 times upper limit of normal value; Serum creatinine \> 1.5 times upper limit of normal value;