NEURO - Prognostication Using Late Somatosensory Evoked - Potentials (NCT07506928) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
NEURO - Prognostication Using Late Somatosensory Evoked - Potentials
France50 participantsStarted 2026-06-30
Plain-language summary
The main aim of this study is to develop a new technique for the passive diagnosis of cognitive-motor dissociation, with the detection of motor intention in a comatose patient by analysing the EEG signal and in particular the ERD/ERS amplitudes in the motor cortex after stimulation of the median nerve.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Patients must be aged 18 years or over;
* Patients must be admitted to the intensive care unit with a cerebrovascular pathology;
* Patients must be in a comatose state with a Glasgow score strictly less than 8, 24 hours after stopping sedation.
* Representative of the patient informed of the research and not objecting to it, information and collection of the participant's non-objection if recovery of the ability to understand the content of the information note,
* The patient is a recipient of or affiliated with a social security scheme.
Exclusion Criteria:
* Bilateral lesions of the motor cortex or cortico-spinal fasciculus,
* Cutaneous infection of the scalp or any other lesion making surface electroencephalography impossible,
* Patient whose short-term survival (48 - 72 hours) seems compromised,
* Severe peripheral neuromyopathy,
* Severe Acute Respiratory Distress Syndrome at the time of screening,
* Hearing-impaired patients with hearing aids,
* Pregnant or breastfeeding woman,
* Patient under legal protection (persons deprived of their liberty or under guardianship).