Effect of Aromatherapy on Pain and Anxiety During Orthodontic Extraction of Maxillary Premolars. (NCT07506135) | Clinical Trial Compass
CompletedNot Applicable
Effect of Aromatherapy on Pain and Anxiety During Orthodontic Extraction of Maxillary Premolars.
India21 participantsStarted 2025-11-20
Plain-language summary
The goal of this randomized placebo-controlled split-mouth clinical trial is to determine whether aromatherapy using lemongrass essential oil can reduce pain, dental anxiety, and physiological stress responses during orthodontic extraction of maxillary premolars .
The main questions it aims to answer are:
* Does aromatherapy reduce pain perception during and after tooth extraction as measured by the Visual Analog Scale (VAS)?
* Does aromatherapy reduce dental anxiety and improve oral health-related quality of life during the extraction procedure as measured by the Modified Dental Anxiety Scale (MDAS-DEP) and Oral Health Impact Profile-14 (OHIP-14)?
Who can participate
Age range
12 Years – 25 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients indicated for bilateral orthodontic extraction of maxillary first or second premolars
* Age 12 to 25 years
* Willing to provide informed consent/assent as applicable
Exclusion Criteria:
* Use of medication within 15 days before the study
* Hypersensitivity to drugs, substances, or materials used in the trial
* Smokers
* Pregnancy or lactation
* Inability to complete the questionnaire
* Preoperative inflammatory or infectious condition
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Pain perception during and after tooth extraction
Timeframe: Peri-procedural (during local anesthesia administration and forceps application), and at 2 hours, 12 hours, 24 hours, and 48 hours post-procedure
2
Dental anxiety during extraction procedure
Timeframe: Baseline (pre-procedure) and immediately post-procedure (within 30 minutes after extraction)
3
Oral health-related quality of life following extraction
Timeframe: 24 hours post-procedure
Trial details
NCT IDNCT07506135
SponsorPostgraduate Institute of Dental Sciences Rohtak