Pre-etched Bioactive Versus Resin- Based Fissure Sealant for Permanent Molars Affected With Molar Incisor Hypomineralization (MIH): a Randomized Clinical Trial

Inclusion Criteria: * 6-12-year-old patients with at least one fully erupted first permanent molar (FPM) diagnosed with MIH defects (White, creamy, or yellow to brownish opacities greater than one millimetre) without posteruptive enamel breakdown or caries (ICDAS code 0 or 1). * Non -contributory medical history * Children must exhibit sufficient cooperation for treatment. * FPMs status of eruption must allow for proper isolation. Exclusion Criteria:- * Medically compromised patient.- Partially erupted MIH first permanent molars that could not be sufficiently isolated. * Carious molars. * Restored MIH molars. * Sealed MIH molars. * MIH molars with extensive enamel breakdown that requires restoration. * MIH molars planned for extraction (compensatory or balancing extraction) as part of elective extraction plan of MIH molars with poor long-term prognosis. * Molars affected with other enamel defects ((e.g., amelogenesis imperfecta or fluorosis) * Non-MIH affected molars. * Parents did not consent for treatment. * Child not sufficiently cooperative for treatment.