Ischemic Preconditioning in Resistance Exercise in Older Women (NCT07497659) | Clinical Trial Compass
CompletedNot Applicable
Ischemic Preconditioning in Resistance Exercise in Older Women
Brazil30 participantsStarted 2025-05-28
Plain-language summary
This study investigates whether ischemic preconditioning (IPC) can reduce cardiac demand after resistance exercise in older women.
Aging is associated with increased cardiovascular stress, especially due to elevated blood pressure and cardiac demand during and after exercise. Strategies that can reduce this overload may improve exercise safety in older women.
This is a randomized, single-blind, crossover clinical trial involving 30 women aged 60 years or older. Participants perform two conditions: ischemic preconditioning (IPC) and a sham condition (SHAM), followed by a standardized resistance exercise session.
The primary outcome is cardiac workload, assessed by the rate-pressure product (systolic blood pressure × heart rate) during post-exercise recovery. Secondary outcomes include blood pressure, heart rate, and heart rate recovery.
The results of this study may contribute to safer exercise strategies for older women.
Who can participate
Age range
60 Years – 70 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Female participants aged 60 years or older
* Physically independent
* Engaged in regular physical activity (at least two sessions per week for the last three months)
* Cleared for exercise participation by a cardiologist following clinical evaluation
* Able to safely perform resistance exercise
* Provided written informed consent
Exclusion Criteria:
* \- History of cardiovascular events such as myocardial infarction or stroke
* Uncontrolled hypertension (≥160/105 mmHg)
* Diabetes mellitus
* Current smoking or alcohol abuse
* Musculoskeletal limitations that impair exercise performance
* Cognitive or communication impairments that interfere with understanding instructions
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.