Determinants of Physical Frailty in Parkinson's Disease: A Multi-Factorial Analysis (NCT07488364) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Determinants of Physical Frailty in Parkinson's Disease: A Multi-Factorial Analysis
100 participantsStarted 2026-03-30
Plain-language summary
The aim of this study is to examine the associations between motor imagery capacity, body awareness (interoceptive awareness), kinesiophobia, physical activity level, and symptom severity in individuals with Parkinson's disease. In addition, the study aims to evaluate the relationships between these variables and physical frailty. This cross-sectional observational study will provide insight into the biopsychosocial factors associated with frailty in Parkinson's disease.
Who can participate
Age range
40 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Clinically diagnosed Parkinson's disease
Hoehn and Yahr stage 1-3
Age between 40 and 85 years
Adequate cognitive function (Mini-Mental State Examination \[MMSE\] score ≥ 24)
Patients attending the Movement Disorders Outpatient Clinic of the Neurology Department
Ability to understand study procedures and provide informed consent
Exclusion Criteria:
* Presence of psychiatric disorders (major depression, psychotic disorders)
Diagnosis of advanced dementia
Presence of severe cardiovascular or respiratory disease, or uncontrolled chronic systemic conditions (diabetes mellitus, hypertension)
Presence of additional neurological or orthopedic conditions that may affect assessment performance
Severe visual or hearing impairments that could interfere with testing procedures
Inability to cooperate adequately with the physiotherapist during assessments
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Vividness of Movement Imagery Questionnaire-2 (VMIQ-2) Total and Subscale Scores
Timeframe: Baseline (at the time of questionnaire administration)
2
Multidimensional Assessment of Interoceptive Awareness-2 (MAIA-2) Total and Subscale Scores
Timeframe: Baseline (at the time of questionnaire administration)
3
Fried Frailty Phenotype (FFP) Classification and Total Criteria Score
Timeframe: Baseline (at the time of physical and questionnaire-based assessment)