RecruitingNot Applicable

Multimodal Assessment of Malignancy in Atypia of Undetermined Significance in Thyroid Nodules Using Ultrasound and Cytology Whole-Slide Images

China396 participantsStarted 2026-03-01

Plain-language summary

The prospective study aim to develop a multimodal deep learning model that integrates ultrasound images and cytological whole-slide images for more accurate malignant risk prediction of Bethesda III thyroid nodules.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * (a) Patients who underwent fine-needle aspiration of thyroid nodules and received a cytological diagnosis of Bethesda Ⅲ. * (b) Patients who subsequently underwent thyroid surgery with a definitive histopathological diagnosis of benign or malignant lesions,. * (c) Availability of at least one ultrasound image acquired prior to surgery. Exclusion Criteria: * (a) Patients without confirmation by surgical pathology,. * (b) Patients without any available or usable ultrasound images.

What they're measuring

Pathological diagnosis.

Timeframe: One month after the surgery.

Trial details

NCT IDNCT07488325

SponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06-30

Contact for this trial

Jingliang Ruan, Ph.D.

+8613694202230 ruanjl3@mail.sysu.edu.cn

View on ClinicalTrials.gov More Thyroid Nodule trials