Not Yet RecruitingPhase 2/3

A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation

United States150 participantsStarted 2026-04-15

Plain-language summary

The purpose of this study is to provide preliminary evidence for the efficacy of 12 weeks of vagal nerve stimulation (VNS) and nicotine replacement therapy (NRT) for increasing smoking abstinence rates.

Who can participate

Age range18 Years

SexALL

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Exclusion criteria

✕. Reliable forms of contraception include oral contraception, diaphragm or condom (with spermicide), injections, intrauterine devices, surgical sterilization, and abstinence. The study does not include vulnerable populations.
✕. Specifically, the study does not include fetuses, neonates, pregnant women, children (\<18 years of age), prisoners, institutionalized individuals, or other vulnerable populations.

What they're measuring

Smoking Abstinence

Timeframe: week 12

Trial details

NCT IDNCT07487818

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-01-15

Contact for this trial

Shawn Fokken, CCRP

507-538-7820 RSTGIMRESStudies@mayo.edu

View on ClinicalTrials.gov More Smoking Cessation trials