CompletedPhase 3

Soaked Pharyngeal Packing Agents in Septoplasty

Egypt65 participantsStarted 2026-03-20

Plain-language summary

Postoperative sore throat (POST) is a frequent and distressing complication after general anesthesia with endotracheal intubation, particularly in nasal surgery for example, functional endoscopic sinus surgery, septoplasty, or septo-rhinoplasty, where pharyngeal packing is routine. While pharyngeal packs may reduce blood ingestion, they may exacerbate POST, warranting effective pharmacologic prophylaxis. This study assesses the efficacy of dexamethasone-soaked pharyngeal packs in reducing incidence of POST in patients undergoing elective septoplasty surgeries.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults aged 18 to 65 years, * Both male and female, * Classified as American Society of Anesthesiologists (ASA) physical status I to III, and * Scheduled for elective septoplasty. Exclusion Criteria: * Preoperative sore throat, * Recent upper respiratory infections, * Anticipated difficult airway, * Existing digestive, respiratory, or cervical conditions, * Regular smoking, * Steroid use within 48 hours prior to surgery, and * Pregnancy. * Patients on chronic corticosteroid therapy, antitussives, or antihypertensive medications * With known effects on airway reactivity or bleeding risk, * Those with uncontrolled hypertension, or * With known allergies to any of the study medications or their components

What they're measuring

Postoperative sore throat (POST) score: 4-point scale as 0 for no sore throat (better outcome), and 3 for severe sore throat associated with hoarseness (worse outcome).

Timeframe: 1 hour

Trial details

NCT IDNCT07486544

SponsorAssiut University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04-25