A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease (NCT07483203) | Clinical Trial Compass
RecruitingNot Applicable
A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease
United States600 participantsStarted 2026-04-28
Plain-language summary
The purpose of this study is to characterize pulmonary hemodynamic profiles, with a focus on PVR subtypes, in patients with left-sided valvular heart disease undergoing aortic or mitral valve intervention, and to identify patterns predicting reversibility of TR and RV dysfunction.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* ≥18 years old; AND
* Scheduled for valve procedures
Exclusion Criteria:
* Congenital heart disease (except for bicuspid aortic valve), OR
* Carcinoid heart disease, OR
* Valvular mass, OR
* Endocarditis, OR
* Any other condition that, in the opinion of the investigator, would impair their ability to complete the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is looking at pulmonary vascular disease alongside valvular heart disease — does my specific valve condition and any pulmonary vascular involvement make me a good candidate to discuss this study with my care team?
2Since this trial is measuring tricuspid regurgitation reduction and right ventricular function improvement, can you help me understand how my current tricuspid valve and right heart function compare to what this study is tracking?
3This appears to be an observational or non-interventional study (Phase NA) — does that mean participation would mainly involve extra monitoring or tests, and how much time or travel would that realistically add to my existing care schedule?
4Are there standard treatments or procedures for my valvular heart disease that I should consider first, before or instead of enrolling in a study like this?
5Since the study is actively recruiting right now, how soon would we need to make a decision about whether to explore this, and what information would you need from my recent test results to have that conversation?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.