Not Yet RecruitingNot Applicable

A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease

United States600 participantsStarted 2026-05

Plain-language summary

The purpose of this study is to characterize pulmonary hemodynamic profiles, with a focus on PVR subtypes, in patients with left-sided valvular heart disease undergoing aortic or mitral valve intervention, and to identify patterns predicting reversibility of TR and RV dysfunction.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ≥18 years old; AND * Scheduled for valve procedures Exclusion Criteria: * Congenital heart disease (except for bicuspid aortic valve), OR * Carcinoid heart disease, OR * Valvular mass, OR * Endocarditis, OR * Any other condition that, in the opinion of the investigator, would impair their ability to complete the study

What they're measuring

Tricuspid Regurgitation (TR) reduction

Timeframe: Baseline, 12 months

Right Ventricular function improvement

Timeframe: Baseline, 12 months

Trial details

NCT IDNCT07483203

SponsorMayo Clinic

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-05

Contact for this trial

Annabelle Fuenffinger

507-422-3801 fuenffinger.annabelle@mayo.edu

View on ClinicalTrials.gov More Pulmonary Vascular Disease trials