Evaluation of Spasticity, Neuropathic Pain, and Gait Analysis in Stroke Patients Receiving Tolper… (NCT07482618) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Evaluation of Spasticity, Neuropathic Pain, and Gait Analysis in Stroke Patients Receiving Tolperison Therapy After Botulinum Toxin Injection
Turkey (Türkiye)40 participantsStarted 2025-08-13
Plain-language summary
Tolperison is an antispastic agent used in the treatment of spasticity. Studies on tolperison are limited, and the literature on its effectiveness against spasticity and neuropathic pain is also limited.
Who can participate
Age range
18 Months – 80 Months
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Ability to stand
* History of previous hemorrhagic or ischemic stroke
* Stroke-related spasticity (MAS ≥2)
* Men and women aged 18-80 years
* Agreement to participate in the study
Exclusion Criteria:
* Diabetes patients
* people who have undergone orthopedic surgery
* Individuals with non-stroke neurological diseases
* Those receiving oral antispastic treatment (non-tolperison medications)
* Those who have undergone surgery for spasticity
* Individuals lacking orientation and cooperation
* Those undergoing surgery, such as with intrathecal baclofen
* Individuals receiving medical treatment for neuropathic pain
* Individuals under 18 and over 80 years of age
* History of allergy or hypersensitivity to the medication to be used
* Presence of a fixed contracture in the affected extremity
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Modified Ashworth Scale(MAS)
Timeframe: Time Frame: Baseline (Day O), Day 15, Month 1, and Month 3.
2
Douleur Neuropathique 4 (DN4)
Timeframe: Time Frame: Baseline (Day O), Day 15, Month 1, and Month 3.