FS-LASIK Versus TransPRK for Mixed Astigmatism (NCT07481227) | Clinical Trial Compass
CompletedNot Applicable
FS-LASIK Versus TransPRK for Mixed Astigmatism
Egypt39 participantsStarted 2019-06-15
Plain-language summary
Mixed astigmatism is a type of refractive error in which the two principal steep and flat meridians focus the light in front and behind the retina, respectively.1 Laser vision correction (LVC) for mixed astigmatism is challenging as it involves a bitoric ablative pattern to flatten the steepest meridian and steepen the flattest one. The aim of the current study was to compare the visual and refractive outcomes of FS-LASIK versus single-step TransPRK for treatment of patients with mixed astigmatism.
Who can participate
Age range
18 Years – 50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Mixed astigmatism (Plus sphere up to +4 diopters D and a minus cylinder up to -6 D).
* Stable refraction.
* Clear cornea.
* Normal corneal tomography.
Exclusion Criteria:
* Corrected distance visual acuity worse than 20/32 Snellen's acuity.
* Difference between manifest and cycloplegic refraction ≥ 1 D.
* Previous corneal or ocular surgeries, other ocular diseases.
* Systemic diseases including diabetes mellitus and autoimmune diseases.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compared FS-LASIK and TransPRK specifically for mixed astigmatism — based on the results, which of those two procedures did your doctor think performed better for someone with my specific type and degree of astigmatism?
2Since this study measured uncorrected distance visual acuity after surgery, what kind of improvement in day-to-day vision without glasses could realistically be expected for someone like me, and how do the results from this trial compare to what I might expect from standard treatment?
3The trial also tracked postoperative refraction, meaning how close patients got to the target prescription — how often did patients in this study end up needing an enhancement or still requiring glasses or contacts after the procedure?
4Because this was a completed trial with no specific phase listed, it may be more of a comparative effectiveness study than an early safety trial — does my doctor feel the evidence from it is strong enough to inform which procedure would be the better choice for my case?
5Are there factors about my eye health, prescription strength, or lifestyle that would make one of these two procedures a clearly better or worse fit for me, based on what this trial found?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.