Not Yet RecruitingNot Applicable

Vegan Diet and Immune-Inflammatory Outcomes in Asthma and Healthy Adults

280 participantsStarted 2026-03

Plain-language summary

This randomized controlled study evaluates the effects of a balanced vegan diet compared with a balanced omnivorous diet on inflammatory and immune response markers and clinical asthma parameters in healthy adults and individuals with mild to moderate asthma, aged 18 to 50. Participants will follow assigned dietary plans for 12 weeks with dietitian support delivered via digital tools.

Who can participate

Age range

18 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: For all groups: * Aged 18-30 years * Willing to adhere to assigned dietary plan (vegan or omnivorous) for 12 weeks * Non-smoker for at least 5 years * Body mass index (BMI) between 18.5 and 24.9 kg/m2 For the asthma group: * Clinical diagnosis of mild or moderate asthma (GINA criteria), made at least 12 months before enrollment * Stable asthma status (no exacerbations or changes in therapy within the past 3 months) * No change in pharmacotherapy during the study period Exclusion Criteria: * Use of systemic corticosteroids (oral or intravenous) within the past 3 months * Ongoing biological therapy for asthma (e.g., anti-IgE, anti-IL-5, anti-IL-4R) * Severe asthma as per GINA criteria * Recent asthma exacerbation requiring hospitalization or steroid burst (\<3 months) * Presence of other chronic autoimmune or inflammatory diseases * Pregnancy or lactation * Active infection or acute illness at the time of recruitment * Adherence to specialized exclusion diets (e.g., ketogenic, low-FODMAP) * History of eating disorders * Inability or unwillingness to participate in follow-up visits or comply with the protocol

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.