By InvitationNot Applicable

5-Year Postoperative Outcomes of Patients Who Completed the CREST Study

United States250 participantsStarted 2025-09-15

Plain-language summary

This study is designed to collect clinical data at 3, 4, and 5 years postoperatively for participants who completed the CREST Study without having secondary IOP-lowering surgery in the study eye(s).

Who can participate

SexALL

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Inclusion criteria

✓. Diagnosis of open-angle glaucoma (OAG) in the study eye(s), including pigmentary and pseudoexfoliative glaucoma, at the time of CREST enrollment
✓. Completed participation in CREST
✓. Provide signed written consent using the Institutional Review Board (IRB)/Ethics Committee (EC) approved study-specific informed consent form (ICF)
✓. Ability, comprehension, and willingness to follow study instructions

Exclusion criteria

✕. Systemic disease that, in the opinion of the Investigator, would put participant's health at risk and/or prevent completion of required study visits
✕. Early termination from CREST
✕. Secondary surgical intervention for long-term IOP control in the study eye(s)

What they're measuring

Mean change in intraocular pressure (IOP)

Timeframe: From before bio-interventional cyclodialysis to 60 months after surgery

Trial details

NCT IDNCT07480343

SponsorIantrek, Inc.

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2030-12

View on ClinicalTrials.gov More Open-angle Glaucoma (OAG) trials